GLOAGUEN A, POUESSEL G, CESAREO E, VAUX J, VALDENAIRE G, GANANSIA O, RENOLLEAU S, BEAUDOUIN E, LEFORT H, MEININGER C. Management of anaphylaxis in emergency medicine. Med Emergency, MJEM 2017; 25:4-24.
Key words: allergy, anaphylaxis, emergency medicine, epinephrine, guidelines
- Authorsâ€™ affiliation
- Article history / info
- Conflict of interest statement
Service mÃ©dical dâ€™urgence, Brigade de sapeurs-pompiers de Paris,
1 place Jules Renard, 75017 Paris, France.
Received: Nov. 5, 2016
Translated: Jan. 10, 2017
Revised: Feb. 15, 2017
Accepted: Mar. 15, 2017
These formalized expert guidelines were written by the French Society of Emergency Medicine (SFMU), in partnership with the French Allergology Society (SFA) and the French Speaking Group in Pediatric Intensive Care and Emergency (GFRUP). Their goal is to educate emergency physicians to early diagnosis of this potentially fatal reaction of severe hypersensitivity, the specific features associated with age, and risk factors identification. Anaphylaxis diagnosis is clinical and used Sampsonâ€™s clinical criteria. The authors offer helps sheets for emergency medical services dispatch and triage criteria for emergency department nurses. As underlined by the international guidelines, the main treatment is early administration of intramuscular epinephrine. If an epinephrine auto-injector is available, the emergency medical services dispatch center on-call physician (112-call) should encourage its immediate use. The second line of treatment is based on the eviction of the triggering factor, the appropriate waiting position, oxygen therapy, and depending on the symptoms, fluid therapy, bronchodilator and epinephrine nebulization. The severity of the prognosis and the unpredictability of developments justify the deployment of a mobile intensive care unit. A minimum six-hour hospital observation is indicated. Tryptase kinetics evaluation contributes to a posteriori diagnosis. At emergency department discharge, the patient must have a prescription of an emergency kit (containing two epinephrine auto-injectors and Î²2-agonists), written instructions and a detailed written hospital report. A specialized consultation with an allergologist is essential after the emergency department discharge.
*This article was initially published as a French version in Annales FranÃ§aises de MÃ©decine dâ€™Urgence (Gloaguen A, Poussel G, Cesareo E, et al. Ann Fr Med Urg 2016; 6: 342-64; erratum published in Ann Fr Med Urg, Erratum to: Prise en charge de lâ€™anaphylaxie en mÃ©decine dâ€™urgence. Recommandations de la SociÃ©tÃ© franÃ§aise de mÃ©decine dâ€™urgence (SFMU) en partenariat avec la SociÃ©tÃ© franÃ§aise dâ€™allergologie (SFA) et le Groupe francophone de rÃ©animation et dâ€™urgences pÃ©diatriques (GFRUP), et le soutien de la SociÃ©tÃ© pÃ©diatrique de pneumologie et dâ€™allergologie (SP2A)